1. To deceive someone. Refers to "hocus-pocus" and its association with magic and trickery. I bet he's hocusing me with that ridiculous story.

2. To add a drug to something, typically an alcoholic drink. She's acting so strangely that I'm starting to wonder if someone hocused her drink.

3. To cause one to be dazed or disoriented, typically by using drugs. Whatever you gave me earlier totally hocused me—I could hardly get up off the couch!