1. To give one occasion or opportunity for a renewed enjoyment in, enthusiasm for, or appreciation of one's life. A noun or pronoun can be used between "give" and "a." After finding out that the tests came back negative for cancer, I feel as though I've been given a new lease of life!

2. To improve or refurbish something that is worn or old. A noun or pronoun can be used between "give" and "a." That new engine has really given my car a new lease of life.