(a) pox on (someone or something)
dated May someone or something be cursed! A pox on these fools that would stand in my way! Ugh, I've been filling in the wrong form—pox on these confusing tax laws!
pox on someone or something
Fig. A curse on someone or something! (Old. Now usually jocular.) A pox on you, you creep! I've been trying to make this computer work all day. A pox on it!